Etymology From hand + shake. See the appendix for the history of the gesture itself.
1
The grasping of hands by two people when greeting, leave-taking, or making an agreement.
Eccles' handshake, eager and practiced and hard, seems to symbolize for him an embrace. For an instant Rabbit fears he will never let go.1960, John Updike, 'Rabbit, Run', page 88:
2
Computing, Engineering, Mathematics, Natural sciences, Physical sciences, Sciences An exchange of signals between two devices when communications begin in order to ensure synchronization.