First attested in 1600. Borrowed from Italian zebra, from Portuguese zebra, zebro (“zebra”), from Old Galician-Portuguese enzebro, ezebra, azebra (“wild ass”), from earlier cebrario (882), ezebrario (897), from Vulgar Latin *eciferus, from Latin equiferus (“wild horse”) (Pliny), from equus (“horse”) + ferus (“wild”). While the word was traditionally pronounced with a long vowel in the first syllable in standard English, during the twentieth century a vowel shift occurred in regions of England, with the shortening of the first vowel. This pronunciation is now used throughout the UK and most Commonwealth nations. The long-vowel pronunciation remains standard in Canadian and American English and is used in the UK only by some older, conservative RP speakers. (unlikely diagnosis): Originates in the advice often given to medical students, "when you hear hoofbeats, think of horses, not zebras". (referee): In reference to the black and white striped shirts they wear.
Medicine, SciencesSlang An unlikely diagnosis, especially for symptoms probably caused by a common ailment.
"It's a zebra! George. OK, I should explain. A zebra is..." "Medical slang for coming to an exotic diagnosis when a more simple explanation is more likely." "That's right. I was convinced that George, given his age and symptoms, had some kind of cardiac issue. It fit, it made sense. Because I was looking for the obvious when I should have been looking for the zebra! George is just having an allergic reaction to a combination of chemicals from all the stains and paints he's been using in the garage."2005 March 7, “Apologies and Rememberances”, in Good Witch, season 1, episode 2 (TV), spoken by Dr. Sam Radford and Cassie Nightingale (James Denton and Catherine Bell), via Hallmark:
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Medicine, SciencesBroadly Someone who has Ehlers-Danlos syndrome or hypermobility spectrum disorder
EDS charities around the world use a zebra logo to promote the idea that sometimes it really is that ‘rare’ condition.2020, Pharmaceutical Technology:
“I was told in medical school, ‘when you hear hoofbeats think horses, not zebras,’” she says. Many trainee doctors receive the same advice – when a patient presents with symptoms, “look for the common thing.” That’s why EDS patients commonly refer to themselves as zebras – and also use the fabulous collective noun “dazzle.” The name represents rarity and evokes the stripy stretch marks that are a common feature on EDS skin.2022 December 24, CNN:
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Derogatory, Ethnic, Slang, Slur A biracial person, specifically one born to a Sub-Saharan African person and a white person.
“People change countries for all kinds of reasons,” Ross tells me. “But at least one of them was that she had this light-skinned, mixed-race child who had already been called a zebra at school.”2021 April 10, Alex Clark, “‘I’m 51, I can say what I want’: Leone Ross has overcome her fears”, in The Guardian:
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Informal A zebra cichlid (Amatitlania nigrofasciata).
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Any of various papilionid butterflies of the subgenus Paranticopsis of the genus Graphium, having black and white markings.
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A zebra crossing.
On his way home he'd picked up two economy-sized bags of tortilla chips, and had dropped both when a twat in a Lexus honked him on a zebra . . .2010, Mick Herron, Slow Horses, page 247:
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Board games, Chess, Games A fairy chess piece that is moved three squares in one direction and two at right angles to that direction in a single move, leaping over any intervening pieces.