retrosynthesis
nounEtymology From retro- + synthesis.
1
Chemistry, Natural sciences, Organic chemistry, Physical sciences The prediction of precursors (intermediates and reactants), given the products of a synthesis reaction.
- 1983, Francis A. Carey, Richard J. Sundberg, Advanced Organic Chemistry: Reactions and synthesis, Plenum Press, page 578, The retrosyntheses shown in Scheme 11.11 correspond to the syntheses in Schemes 11.12 and 11.13.
- The retrosyntheses shown in Scheme 2 lead directly to acetylene-type retrons (14)-(16) (path a) or implicate the use of Dewar o-xylylene (17) (path b) and the smaller retrons (18)-(20); the latter path was the route we elected to pursue (Scheme 3).1991, Australian Journal of Chemistry, Volume 44, CSIRO, page 1294:
1 more example
- For example, the above mentioned retrosynthesis of nacre [132] is as much bio-inspired as is the crystallization in presence of hydrophilic polymers [44], although in the first case, the original biomineral structure is reproduced, whereas in the latter case, no biomineral is reproduced but complex crystal morphologies are obtained.2007, Helmut Cölfen, “Bio-inspired Mineralization Using Hydrophilic Polymers”, in Kensuke Naka, editor, Biomineralization II: Mineralization Using Synthetic Polymers and Templates, Springer, page 25:
- Synonyms
- retrosynthetic analysis
- Derived terms
- bioretrosynthesis, retrosynthesize, retrosynthetic
- Related terms
- retrobiosynthesis, reverse engineering, synthon