shotgun sequencing
nounEtymology Formed through analogy with the effect of a shotgun blast, which contains many small pellets.
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Biology, Genetics, Medicine, Natural sciences, Sciences A DNA sequencing technique in which a large number of small fragments of a long DNA strand are generated at random, sequenced, and reassembled to form a sequence of the original strand.
- In shotgun sequencing of genomic DNA, fragments of a genome are sequenced and computationally reassembled to determine the genome of an organism2005, Selene K Swanson with Michael P. Washburn, “The continuing evolution of shotgun proteomics”, in Drug Discovery Today, →DOI, page 719: