shotgun proteomics
noun1
Biology, Genetics, Medicine, Natural sciences, Sciences A laboratory method for the determining the identities of proteins in a mixture.
- Analogous to (shotgun sequencing), in shotgun proteomics, complex protein mixtures are digested into peptides, analyzed by tandem mass spectrometry, and computer algoriths then map the peptides onto proteins to determine the original content of the mixture.2005, Selene K Swanson, P. Michael, “The continuing evolution of shotgun proteomics”, in Drug Discovery Today: