urethritis🔊nounUK /ˌjʊəɹɪˈθɹaɪtɪs/ · US /ˌjʊɹəˈθɹaɪtɪs/Etymology From urethr- + -itis.1Medicine, Pathology, Sciences Usually Inflammation of the urethra, a finding possible in many diseases (e.g., STI and non-STI, including UTI) but often in gonorrhea and chlamydia.