titin
noun/ˈtaɪtɪn/
Etymology From titan + -in. From being a titanic (titan) protein (-in), a very large protein, the largest known prior to the discovery of PKZILLA.
1
Biochemistry, Biology, Chemistry, Microbiology, Natural sciences, Physical sciences A protein important in the contraction of striated muscle tissues.
- In order to measure the pattern of force-dependent stretching of TR, we designed a DNA construct encoding for I27 2 -T R -I27 2 [TR flanked by two molecules of the I27 (27th immunoglobular domain of human cardiac titin), which has well-characterized mechanical properties.]2009 January 30, Armando del Rio et al., “Stretching Single Talin Rod Molecules Activates Vinculin Binding”, in Science:
- Synonyms
- connectin, methionylthreonyl...arginylserylisoleucine
- Derived terms
- titinopathy, TTN