progeria
noun/pɹoʊˈd͡ʒɪ(ə)ɹiə/
Etymology From Ancient Greek προγήρως (progḗrōs, “prematurely old”) + -ia.
1
Medicine, Pathology, Sciences An extremely rare genetic condition wherein symptoms resembling aspects of aging are manifested at an early age.
- Hutchinson–Gilford syndrome or progeria (derived from pro, before, and geras, old age) is characterized by premature ageing (Fig. 18.1) and the early onset of age-related symptoms such as joint restriction and cerebral and myocardial infarction. Progeria occurs in about one in eight million people (DeBusk, 1972), but the true incidence may be somewhat higher (Sarkar and Shinton, 2001).2004, E. S. Roach, “18: Hutchinson-Gilford progeria syndrome”, in E. Steve Roach, Van S. Miller, editors, Neurocutaneous Disorders, page 150:
- Hutchinson-Gilford progeria is a syndrome commonly characterized by accelerated aging. Children affected by progeria have a life expectancy of approximately 13 years. Progeria results from damage to the LMNA gene that codes for the protein lamin A.2007, Carie Ann Braun, Cindy Miller Anderson, Pathophysiology: Functional Alterations in Human Health, page 436:
1 more example
- Hutchinson Gilford progeria syndrome (progeria) is a rare childhood disease, affecting 1 in 4 million births worldwide (Hennekam, 2006) and recapitulates certain aspects of the normal aging process at an accelerated rate.2015, Ingrid A. Harten, Michelle Olive, Thomas N. Wright, “16: Vascular Disease in Hutchinson Gilford Progeria Syndrome and Aging: Common Phenotypes and Potential Mechanisms”, in Matt Kaeberlein, George Martin, editors, Handbook of the Biology of Aging, 8th edition, page 434:
- Synonyms
- Benjamin Button disease, Hutchinson-Gilford progeria, Hutchinson-Gilford progeria syndrome, Hutchinson–Gilford syndrome
- Derived terms
- progeric, progerin, progeroid, pseudoprogeria
- Related terms
- Werner syndrome