pathoprogression
nounEtymology From patho- + progression.
- This leads us to speculate that lysosomal impairment due to diminished GCase expression and enzyme activity as shown in AD could also affect cell-to-cell transmission of Aβ aggregates and the pathoprogression of AD.2015 December 3, “Lysosomal Enzyme Glucocerebrosidase Protects against Aβ 1-42 Oligomer-Induced Neurotoxicity”, in PLOS ONE, →DOI: