nanoengager
nounEtymology From nano- + engager.
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Biochemistry, Biology, Chemistry, Microbiology, Natural sciences, Physical sciences A nanoparticle which engages certain cells in a process; a nanoscale engager.
- Moreover, the nanoengagers can deliver cytotoxic chemotherapeutics to further improve their therapeutic efficacy. We have demonstrated that effective NK cell activation can be achieved by the spatiotemporal coactivation of CD16 and 4-1BB stimulatory molecules on NK cells with nanoengagers, and the nanoengagers are more effective than free antibodies.2020 July 3, Kin Man Au, Steven I. Park, Andrew Z. Wang, “Trispecific natural killer cell nanoengagers for targeted chemoimmunotherapy”, in Science Advances, volume 6, number 27, →DOI, page 1: