monoagent
nounEtymology From mono- + agent.
1
Medicine, Sciences Any chemotherapeutic agent that works alone
- ONC201 is a stable, orally active, blood brain barrier-penetrable compound that has demonstrated p53-independent anti-cancer activity as a monoagent and a combination in several preclinical models that include glioblastoma, breast cancer, colon cancer, lung cancer, lymphoma, and other tumors [1, 10, 11 ].2015 November 19, “First-In-Class Small Molecule ONC201 Induces DR5 and Cell Death in Tumor but Not Normal Cells to Provide a Wide Therapeutic Index as an Anti-Cancer Agent”, in PLOS ONE, →DOI: