misfold
noun/ˈmɪsfoʊld/
Etymology From mis- + fold.
1
An incorrect or abnormal folding.
misfold
verb/mɪsˈfoʊld/
Etymology From mis- + fold.
1
Biochemistry, Biology, Chemistry, Microbiology, Natural sciences, Physical sciences To fold into an unusual or incorrect tertiary structure; misfolded proteins occur in various diseases, including amyloidoses and dementias, although the question of causation versus consequence is not yet definitively answered for dementias.
Of a protein or nucleic acid
- The prionopathies are best known among the neurodegenerative diseases for their ability to misfold, self-propagate, and infect other organisms.2021 March 1, Anderson, K.N.; Overcast, W.B.; Brosch, J.R.; Graner, B.D.; Veronesi, M.C., “Prionopathies and Prionlike Protein Aberrations in Neurodegenerative Diseases”, in American Society of Neuroradiology, volume 11, number 2, →DOI, pages 127-148: