frameshift
verbEtymology From frame + shift.
1
To use a starting point for translating a series of nucleotides that is off by an amount not divisible by three, resulting in an entirely distinct set of codons.
- Commonly, there are stimulatory signals in mRNA distinct from the shift site that greatly increase the level of frameshifting at the shift site.2003, Jacques Lapointe, Lea Brakier-Gigras, Translation Mechanisms, →ISBN, page 354:
- Considering these costs, it seems likely that mechanisms may exist to stop frameshifted translation as soon as possible, depending on the frequency of occurrence.2004, DNA and Cell Biology - Volume 23, page 702:
1 more example
- Ribosomal frameshifting at a particular site can yield two protein products from one coding sequence or one protein product from two overlapping open reading frames.2006, De-Shuang Huang, George William Irwin, Computational Intelligence and Bioinformatics, →ISBN: