filgotinib
noun1
Medicine, Pharmacology, Sciences A medication, belonging to the class of Janus kinase inhibitors, used for the treatment of rheumatoid arthritis.
- Both upadacitinib and filgotinib have been referred to as “second-generation jakinibs” since they both preferentially inhibit JAK1 in vitro but their clinical efficacy and safety, to a large extent, is similar to pan-jakinibs in RA, although anemia and herpes zoster are seen less often with filgotinib.2021 December, Christine Liu, Jacqueline Kieltyka, Roy Fleischmann, Massimo Gadina, John J. O’Shea, “A Decade of JAK Inhibitors: What Have We Learned and What May Be the Future?”, in Arthritis & Rheumatology, volume 73, number 12, →DOI, page 2168: