fedratinib
noun1
Medicine, Pharmacology, Sciences A medication belonging to the class of Janus kinase inhibitors, used for the treatment of myeloproliferative diseases including myelofibrosis.
- Fedratinib is a selective JAK2 inhibitor approved for primary and secondary myelofibrosis. An important AE observed with fedratinib is Wernicke’s encephalopathy, which has been observed in patients taking the highest daily dosage (500 mg) (70).2021 December, Christine Liu, Jacqueline Kieltyka, Roy Fleischmann, Massimo Gadina, John J. O’Shea, “A Decade of JAK Inhibitors: What Have We Learned and What May Be the Future?”, in Arthritis & Rheumatology, volume 73, number 12, →DOI, page 2172: