From outside of an organism or from the substrate.
Work historically performed by toxicologists has provided an impressive list of endogenous and exobiotic compounds termed peroxisome proliferators (PP) which were so named for their ability following chronic high dose administration to rodents, to increase the number and activities of an essential intracellular organelle termed the peroxisome.2000, Mohammed Y. Kalimi, William Regelson, Dehydroepiandrosterone (DHEA), →ISBN:
Little is known about the clinical safety of exobiotic polymers.2012, Henrik S. Thomsen, Robert N. Muller, Robert F. Mattrey, Trends in Contrast Media, →ISBN, page 185:
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Due to soil types and other exobiotic factors (e.g^([sic]) water supply and temperature) many microenvironments may be present, leading to the need for polysaccharides adapted to these conditions.2013, B.B. Biswas, H.K. Das, Plant-Microbe Interactions, →ISBN, page 74:
In any case, OXLs from C^α-trisubstituted residues were extensively employed for the preparation of enantiomerically α-amino acid derivatives and C^α-tetrasubstituted α-amino acids (in the latter experiments, also in the context of investigations in the prebiotic and exobiotic fields).2015, Maxim Ryadnov, Ferenc Hudecz, Amino acids, peptides and proteins: Volume 40, →ISBN, page 18:
2
Of or pertaining to exobiology.
For example, terran contamination could result in the introduction of exobiotic organisms, the initiation of chemical reactions or changes, or the mutation of either 12 indigenous or exogenous organisms.1981, Proceedings - Volume 23, page 109:
Around me were computer databases filled with records of innumerable galaxies, exobiotic life forms and extraterrestrial cultures.2002, Linda Johnsen, The Living Goddess, →ISBN:
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Lake Vostok may represent the closest analog to the subglacial environments that existed during the Neoproterozoic Era on Earth or exobiotic environments on Mars or Europa, the ice-covered moon of Jupiter.2007, K. E. Peters, C. C. Walters, J. M. Moldowan, The Biomarker Guide, →ISBN:
Some kind of exobiotic plague had run through the animal stock seven months back, and half of them had died.2012, Michael Reaves, Steve Perry, Star Wars: Death Star, →ISBN, page 77:
Derived terms
exobiotically
exobiotic
noun
Etymology From exo- + biotic.
1
Medicine, Sciences An exobiotic substance, especially one that influences the functioning of an organ or biological process.
We have listed an example of an exobiotic which influences each identified step, but it should be remembered that this is far from an exhaustive list of the exobiotics which affect adrenal function.1996, Philip W. Harvey, Adrenal in Toxicology: Target Organ and Modulator of Toxicity, →ISBN, page 74:
The liver is exposed to millions of antigens and exobiotics. If every contact would stimulate the immune system, the liver would be in a permanent state of inflammation.2010, Pere Ginès, Chronic Liver Failure: Mechanisms and Management, page 43:
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ADME and chemical reactivity-related toxicity is low, while biological receptor activity is of higher dimension in chemistry space, and this is partly explainable by evolutionary pressures on ADME to deal with endobiotics and exobiotics.2006, Sarfaraz K. Niazi, Handbook of Preformulation: Chemical, Biological, and Botanical Drugs: