estradiol
nounUS /ˌɛs.tɹəˈdaɪˌɔl/
Etymology Internationalism. From estratriene (“estra(triene)”) + diol. By surface analysis, estra- + di- + -ol.
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Biochemistry, Biology, Chemistry, Microbiology, Natural sciences, Physical sciences US A natural estrogenic hormone that is a phenolic alcohol estra-1,3,5-triene-3,17-diol (C₁₈H₂₄O₂) secreted chiefly by the ovaries of all vertebrates, that is a major and the most potent of the naturally occurring estrogens; the semisynthetic esterified compound is used medicinally to treat estrogen deficiency and breast cancer.
- Gender-affirming hormone therapy may involve testosterone for trans people assigned female at birth (AFAB) and estradiol and anti-androgens for trans people AMAB.2021, Jane Y. Xu, Michelle A. O’Connell, Lauren Notini, Ada S. Cheung, Sav Zwickl, Ken C. Pang, “Selective Estrogen Receptor Modulators: A Potential Option For Non-Binary Gender-Affirming Hormonal Care?”, in Front Endocrinol, →DOI:
- Derived terms
- cloxestradiol, estradiol benzoate, estradiol undecylate, estradiol valerate, estramustine, estrapronicate, ethinylestradiol, fluorestradiol, fluoroestradiol, methylestradiol, mifepristone, quinestradol