deimmortalize
verbEtymology From de- + immortalize.
1
Biology, Natural sciences To make a cell subject to normal apoptosis
- After SV40 T-Ag was removed to deimmortalize the cells, telomerase activity was reduced to its original level before immortalization and decreased with passages just the same as primary DFCs. These results suggest that piggyBac immortalization system could be a potential strategy to amplify primary cells, which is critical for regenerative research and further clinical application.2015 July 15, “TrAmplification of Human Dental Follicle Cells by piggyBac Transposon - Mediated Reversible Immortalization System”, in PLOS ONE, →DOI:
- Related terms
- deimmortalization