codepletion
nounEtymology From co- + depletion.
1
Biology, Natural sciences The depletion of one substance in conjunction with the depletion of another.
- We found that codepletion of ERG/FLI-1 resulted in inhibition of NR4A1 dependent H3K27ac at distal enhancers of all three induced genes (Fig 6D) and also strongly prevented NR4A1 dependent recruitment of p300 (Fig 6E).2016 March 4, “Genome Wide Mapping of NR4A Binding Reveals Cooperativity with ETS Factors to Promote Epigenetic Activation of Distal Enhancers in Acute Myeloid Leukemia Cells”, in PLOS ONE, →DOI: