bandshift assay
noun1
Biochemistry, Biology, Chemistry, Microbiology, Natural sciences, Physical sciences A type of assay using gel electrophoresis, in which the mobility of a DNA or RNA probe alone is compared to its mobility in combination with a particular protein, so as to measure the degree and nature of binding between the protein and DNA or RNA.
- In bandshift assays, hPot1p bound to the G-rich strand of human telomeric DNA.2001 May 11, Peter Baumann, Thomas R. Cech, “Pot1, the Putative Telomere End-Binding Protein in Fission Yeast and Humans”, in Science, volume 292, number 5519, →DOI, pages 1171–1175: