anfibatide
noun1
Medicine, Pharmacology, Sciences An antithrombotic agent binding to the GPIbα subunit of the glycoprotein Ib-IX-V complex, purified from the venom of the sharp-nosed viper (Deinagkistrodon acutus).
- Anfibatide is an anticoagulant C-type lectin-like protein purified from the venom of the sharp-nosed viper (Deinagkistrodon acutus). […] The anticoagulant activity of anfibatide is due to its strong binding to human platelet glycoprotein Ib α-chain (GPIbα), which inhibits the binding of GPIbα with von Willebrand factor (VWF) and thrombin^(124,125) (Fig. 6a).2022 June 10, Oliveira, A.L., Viegas, M.F., da Silva, S.L. et al., “The chemistry of snake venom and its medicinal potential”, in Nature Reviews Chemistry, volume 6, →DOI, page 462: